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MiR-25 is overexpressed in both keratinocytes and melanocytes in response to oxidative stress, which decreases the activity of antioxidant enzymes and impairs melanosome transport, leading to redox imbalance [51]

Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia

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[DOI] [PubMed] [Google Scholar] 108.Lasram M.M., Dhouib I.B., Annabi A., El Fazaa S., Gharbi N

Conversely, other studies revealed that the decreased survival of cancer patients is associated with the suppressed expression of GPx2, confirming the tumor-suppressive function of GPx2 (Ren et al